STK40 (SHIK) Protein(S54-34G)
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Description :Full-length recombinant human STK40 (SHIK) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Species :Human
Tag :GST tag
Expression System:Sf9 insect cells using baculovirus
Sequence :Full Length
Genbank Number :NM_032017
Purity :Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability and Shipping :Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Applications :Western Blot
Molecular Weight :~74 kDa
Gene Aliases :RP11-268J15.4; SgK495; SHIK
Scientific Background :STK40 is a serine/threonine-protein kinase 40 that functions in cell division and also to promote efficient cytokinesis. STK40 is also called SHIK (sink- homologous inhibitory kinase) which is expressed in all tisues. STK40 also inhibits TNF-induced NF-kappa-B activation and p53-induced transcription (1).
References :
1. Huang, J.et.al: Identification of a novel serine/threonine kinase that inhibits TNF-induced NF-kappa-B activation and p53-induced transcription. Biochem. Biophys. Res. Commun. 309: 774-778, 2003.
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Research Areas :Ser/Thr Kinases, PKA/PKC Pathway, Neurobiology, ERK/MAPK Pathway, Cardiovascular Disease, Neurobiology, Cardiovascular Disease, ERK/MAPK Pathway, PKA/PKC Pathway, Ser/Thr Kinases