TSSK6 (SSTK) Protein(S23-34G)

TSSK6 (SSTK) Protein(S23-34G)

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Description :Full-length recombinant human TSSK6 (SSTK) protein was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Species :Human

Tag :GST tag

Expression System:Sf9 insect cells using baculovirus

Sequence :Full Length

Genbank Number :NM_032037

Purity :Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability and Shipping :Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications :Western Blot

Molecular Weight :~57 kDa

Gene Aliases :CT72; FKSG82; SSTK; TSSK4; TSSK6

References :
1. Spiridonov, N. et.al: Identification and characterization of SSTK, a serine/threonine protein kinase essential for male fertility. Molec. Cell. Biol. 25: 4250-4261, 2005.

2. Hao, Z. et.al: Expression analysis of the human testis-specific serine/threonine kinase (TSSK) homologues: a TSSK member is present in the equatorial segment of human sperm. Molec. Hum. Reprod. 10: 433-444, 2004.

Scientific Background :TSSK6 or testis-specific serine kinase 6 is a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family which is required for postmeiotic chromatin remodeling and male fertility (1). Tssk6-null spermatozoa have impaired DNA condensation. TSSK6 is highly expressed in testis. TSSK6 is present in the equatorial segment of human sperm (2).

Product Sheets (By Lot #) :

Z1372-4.pdf

Research Areas :Cancer, Cardiovascular Disease, Ser/Thr Kinases, Cancer, Cardiovascular Disease, Ser/Thr Kinases