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  • $127.00


Description :Recombinant Human WISP3 was expressed in E. coli cells.

Species :Human

Tag :

Expression System:E.coli

Sequence :

Genbank Number :O95389

Storage, Stability and Shipping :The lyophilized protein is stable for at least one year from date of receipt at -70oC. Upon reconstitution, this cytokine can be stored in working aliquots at 2o - 8oC for one month, or at -20oC for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Applications :Cell Assay

Endotoxin Level :<1.0 EU/μg of recombinant protein as determined by the LAL method

Molecular Weight :37.1 kDa

Scientific Background :WNT1-inducible-signaling pathway protein 3 (WISP3) is a member of the CCN family of cysteine-rich, glycosylated signalling proteins that mediate several developmental processes, and a member of the WNT1 inducible signalling pathway (WISP) subfamily. Members of this family are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain (IGFBP), von Willebrand factor type C (VWFC) domain, thrombospondin type-1 repeat (TSP type-1) domain, and C-terminal cystine knot-like (CTCK) domain. WISP3 is expressed in mature and fetal kidneys, testis, and in lower levels in the ovary, placenta, prostate, and small intestine. It is necessary for the growth of postnatal skeleton and cartilage homeostasis.

Sample Cell Assay Data :The ED50 was 0.2-0.3 µg/mL as determined by cell proliferation assay

Purity :Recombinant Human WISP3 resolved on a 15% SDS-PAGE gel under reducing conditions and stained with Coomassie Brilliant Blue G-250

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Research Areas :Cancer