VEGFB(V811-40N)

VEGFB(V811-40N)

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Description :Recombinant Human VEGFB was expressed in E. coli cells.

Species :Human

Tag :

Expression System:E.coli

Sequence :

Genbank Number :P49765

Storage, Stability and Shipping :Store at 4oC if entire vial will be used within 2-4 weeks. Store frozen at -20oC for longer periods of time. For long term storage, we recommend adding a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

Applications :Cell Assay

Endotoxin Level :<1.0 EU/μg of recombinant protein as determined by the LAL method

Molecular Weight :19.0 kDa

Gene Aliases  :VEGF-related factor

Scientific Background :Vascular endothelial growth factor B (VEGFB) is a homodimeric, heparin-binding glycoprotein member of the VEGF family of growth factors. Compared to VEGFA, VEGFB’s main role is the maintenance of newly formed blood vessels and is involved in endothelial cell physiology. It is a ligand for vascular endothelial growth factor receptor 1 (VEGFR1) and neuropilin-1 (NRP1), while the binding of neuropilin-1 to VEGFB186 is proteolysis regulated.

Sample Cell Assay Data :Measured in a cell proliferation assay using NIH-3T3 mouse embryonic fibroblast. The ED50 for this effect is < 1ng/ml.

Purity :Recombinant Human VEGFB resolved on a 15% SDS-PAGE gel under reducing conditions and stained with Coomassie Brilliant Blue G-250

Product Sheets (By Lot #) :

G3223-27.pdf

Research Areas :Cancer