HOLIDAY SHIPPING UPDATE: All delivery service requests will not be processed on Wednesday, July 1, 2020 as it is Canada Day holiday. Regular delivery schedule will resume the next business day.
UBE2L3 (UBCH7) Protein(U228-30H)

UBE2L3 (UBCH7) Protein(U228-30H)

  • $105.00


Description :Recombinant full-length human UBE2L3 was expressed in E. coli cells using an N-terminal His tag.

Species :Human

Tag :His tag

Expression System:E.coli

Sequence :Full length

Genbank Number :NM_003347

Purity :Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability, and Shipping :Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications :Western Blot

Molecular Weight :18 kDa

Gene Aliases :E2-F1; L-UBC; UBCH7; UbcM4

Scientific Background :Ubiquitin-conjugating enzyme E2 L3 (UBE2L3) belongs to the ubiquitin-conjugating enzyme family of the ubiquitin-proteasome pathway, facilitating the transfer of activated ubiquitin from ubiquitin-activating enzyme to target proteins with the help of ubiquitin-protein ligases. It specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases and does not function with most RING-containing E3 ubiquitin-protein ligases. Catalyzes 'Lys-11'-linked polyubiquitination in vitro.

References :
1. Nuber U, et al: Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5. J Biol Chem. 1996 271:27105-800

2. David Y, et al: The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines. J Biol Chem. 2010 19;285:85105-604.


Product Sheets (By Lot #) :


Research Areas :Cell Cycle, Neurobiology