HOLIDAY SHIPPING UPDATE: All delivery service requests will not be processed on Friday April 2, 2021 as it is Good Friday holiday. Regular delivery schedule will resume the next business day.
UBE2G1 (UBC7), Active(U221-380H)

UBE2G1 (UBC7), Active(U221-380H)

  • $215.00


Description :Recombinant full-length human UBE2G1 was expressed in E. coli cells using an N-terminal His tag.

Species :Human

Tag :His tag

Expression System:E.coli

Sequence :Full length

Genbank Number :NM_003342

Specific Activity :Sample Activity Plot. For specific information on a given lot, see related technical data sheet.

Purity :Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability, and Shipping :Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications :Ubiquitin Enzyme Assay, Western Blot

Molecular Weight :21 kDa

Gene Aliases :UBC7; E217K; UBE2G

Scientific Background :UBE2G1 (UBC7) or ubiquitin-conjugating enzyme E2G 1 is a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins which are involved in degradation of muscle-specific proteins. UBC7 is highly expressed in skeletal muscle. UBC7 is involved in the selective ubiquitylation of different substrates by the same E3 complex.

References :
1. Mondal, S. et al: A bioluminescent assay for monitoring conjugation of ubiquitin and ubiquitin-like proteins. Anal. Biochem. 510: 41-51, 2016

2. Watanabe, T.K. et al: Molecular cloning of UBE2G, encoding a human skeletal muscle-specific ubiquitin-conjugating enzyme homologous to UBC7 of C. elegans. Cytogenet. Cell Genet. 74: 146-148, 1996

3. David, Y. et al: The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines. Cytogenet. J Biol Chem. 285(12): 8595-8604, 2010

Product Sheets (By Lot #) :


Research Areas :Cancer, Cell Cycle, Neurobiology