UBE2U Protein(U237-30G)

UBE2U Protein(U237-30G)

  • $215.00


Description :Recombinant full-length human UBE2U was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Species :Human

Tag :GST tag

Expression System:Sf9 insect cells using baculovirus

Sequence :Full Length

Genbank Number :NM_152489

Purity :Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability and Shipping :Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications :Western Blot

Molecular Weight :~52 kDa

Gene Aliases :RP4-636O23.1

Scientific Background :UBE2U, or Ubiquitin-conjugating enzyme E2 U, belongs to the ubiquitin-conjugating enzyme family. In the global yeast two-hybrid (Y2H) screens to study the specificity of interactions between catalytic domains of the human E2s with RING-type E3s, the analysis showed the UBE2U had a high-quality and physical interactions with a few E3 ligases (1) and (2).

References :
1. van Wijk SJ, et.al: A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system. Mol Syst Biol. 5:295. doi: 10.1038, 2009.

2. Markson G, et.al: Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. Genome Res. 19 (10):1905-11. doi: 10.1101, 2009.

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Research Areas :Neurobiology, Cell Cycle, Cancer