TNFRSF1B(T863-40BN)

TNFRSF1B(T863-40BN)

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Description :Recombinant Human TNFRSF1B was expressed in E. coli cells.

Species :Human

Tag :

Expression System:E.coli

Sequence :

Genbank Number :P20333

Storage, Stability and Shipping :The lyophilized protein is stable for at least one year from date of receipt at -70oC. Upon reconstitution, this cytokine can be stored in working aliquots at 2o - 8oC for one month, or at -20oC for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Applications :Cell Assay

Endotoxin Level :<1.0 EU/μg of recombinant protein as determined by the LAL method.

Molecular Weight :19.0 kDa

Gene Aliases :sTNF Receptor Type II, sTNFRII, TNFRSF1B, Tumor necrosis factor receptor 2, TNF-RII, TNF-R2, TNFR-II, TNFR75, TNFR80, p80 TNF-alpha receptor, Recombinant Human Tumor Necrosis Factor Receptor Superfamily Member 1B (TNFRSF1B)

Reconstitution Protocol :Reconstitute at 0.1mg/mL in sterile PBS.

Scientific Background :TNFRSF1B is a single-pass type-1 transmembrane protein that functions as a receptor with high affinity for TNFSF2/TNF-alpha . It has been shown that signaling through this receptor regulates various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. Recombinant human TNFRSF1B comprises the extracellular domain (ligand binding) of the TNFRII protein.

Sample Cell Assay Data :The ED (50) was determined by the dose-dependent proliferation of Immortalized human renal proximal tubule cells and was found to be <0.05ng/mL.

Purity :Recombinant Human TNFRSF1B resolved on a 15% SDS-PAGE gel under reducing conditions and stained with Coomassie Brilliant Blue G-250.

Product Sheets (By Lot #) :

G3223-20.pdf

Research Areas :Cancer