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TBCKL Protein(T35-31G)

TBCKL Protein(T35-31G)

  • $314.00


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Description :Full-length recombinant human TBCKL was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Species :Human

Tag :GST tag

Expression System:Sf9 insect cells using baculovirus

Sequence :Full length

Genbank Number :BC009208

Purity :Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability, and Shipping :Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications :Western Blot

Molecular Weight :118 kDa

Gene Aliases :HSPC302

Scientific Background :TBC domain-containing protein kinase-like protein (TBCK) is a Ser/Thr kinase that contains a protein kinase domain, a Rhodanase-like domain and the Tre-2/Bub2/Cdc16 (TBC) domain. TBCK is involved in the regulation of mTOR signaling pathway and plays a role in cell proliferation, cell size, and the organization of actin. 3 isoforms of the human protein are produced by alternative splicing.

References :
1. Liu Y, et al: TBCK influences cell proliferation, cell size and mTOR signaling pathway. PLoS One. 2013 Aug 19;8(8):e71349.

2. http://www.phosphosite.org/proteinAction.do?id=2231&showAllSites=true

Product Sheets (By Lot #) :

U1511-3.pdf

Research Areas :Cancer