Anti-TET3(T638-63R)
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Description :Rabbit Polyclonal Antibody
Species :
Tag :
Expression System:
Sequence :
Specificity :Recognizes the TET3 protein
Cited Applications :WB, ELISA, IF
Cross Reactivity :Human
Host / Isotype / Clone# :Rabbit, IgG
Immunogen :TET3 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TET3
Purification :Affinity chromatography
Stability :Store at 4oC (add 0.1% NaN3) for several months, and at -20oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Sample Data :Western blot analysis of TET3 in SK-N-SH cell lysate with TET3 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
References :1. Howe LR et al: Activation of the MAP kinase pathway by the protein kinase raf. Cell1992; 71:335-42. 2. Langemeijer SM et al: Acquired mutations in TET2 are common in myelodysplastic syndromes. Nat. Genet. 2009; 41:838-42. 3. Schaub FX et al: Clonal analysis of TET2 and JAK2 mutations suggests that TET2 can be a late event in the progression of myeloproliferative neoplasms. Blood 2011; 115:2003-7. 4. Langemeijer SMC et al: TET proteins in malignant hematopoiesis. Cell Cycle 2009; 4044-8. 5. Gu TP et al: The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature 2011; 477:606-10.
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Research Areas :Cancer, Cell Cycle, Cancer, Cell Cycle