STYK1(NOK) Protein(S53-35G)

STYK1(NOK) Protein(S53-35G)

  • $215.00


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Description :Recombinant human STYK1(NOK) (58-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Species :Human

Tag :GST tag

Expression System:Sf9 insect cells using baculovirus

Sequence :58-end

Genbank Number :NM_018423

Purity :Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability and Shipping :Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications :Western Blot

Molecular Weight :~67 kDa

Gene Aliases :NOK; STYK1; DKFZp761P1010; SuRTK106

Scientific Background :STYK1 is belongs to serine/threonine/tyrosine kinase 1 family which play important roles in diverse cellular and developmental processes, such as cell proliferation, differentiation, and survival (1). STYK1 concomitantly activate both MAP kinase and PI3K pathways in stably transfected mouse pre-B cells and STYK1 expression is elevated in 92.3% cancerous tissues in comparison with normal tissues (2).

References :
1. Liu, L. et.al: A novel protein tyrosine kinase NOK that shares homology with platelet-derived growth factor/fibroblast growth factor receptors induces tumorigenesis and metastasis in nude mice. Cancer Res. 64: 3491-3499, 2004.

2. Amachika, T. et.al: Diagnostic relevance of overexpressed mRNA of novel oncogene with kinase-domain (NOK) in lung cancers. Lung Cancer 56: 337-340, 2007.

Product Sheets (By Lot #) :

I159-2.pdf

Research Areas :Cancer, Cell Cycle, Cytoplasmic Tyrosine Kinases, Invasion/Metastasis, Cancer, Cell Cycle, Invasion/Metastasis, Cytoplasmic Tyrosine Kinases