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STK21 (CIT), Active(C52-11G)

STK21 (CIT), Active(C52-11G)

  • $259.00


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Description :Recombinant human STK21 (CIT) (1-449) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Species :Human

Tag :GST tag

Expression System:Sf9 insect cells using baculovirus

Sequence :1-449

Genbank Number :NM_007174

Specific Activity :Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.

Purity :Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability and Shipping :Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications :Kinase Assay, Western Blot

Molecular Weight :~74 kDa

Gene Aliases :CIT; CRIK

Scientific Background :STK21 is a serine/threonine-protein kinase that functions in cell division and also to promote efficient cytokinesis. STK21 is a novel molecular mechanism for a subset of human malformation syndromes of the central nervous system (1). STK21 is also associated with bipolar disorder and risk for schizophrenia. STK21 is a novel partner for the GTP-bound forms of rho and rac (2).

References :
1. Di Cunto, F.et.al: Citron Rho-interacting kinase, a novel tissue-specific ser/thr kinase encompassing the Rho-Rac-binding protein citron. J. Biol. Chem. 273: 29706-29711, 1998.

2. Madaule, P.et.al: A novel partner for the GTP-bound forms of rho and rac. FEBS Lett. 377: 243-248, 1995.

Product Sheets (By Lot #) :

T1028-4.pdf

E3153-8.pdf

Research Areas :Cardiovascular Disease, ERK/MAPK Pathway, Neurobiology, PKA/PKC Pathway, Ser/Thr Kinases, Neurobiology, Cardiovascular Disease, ERK/MAPK Pathway, PKA/PKC Pathway, Ser/Thr Kinases