SR-3576(M35-901)

SR-3576(M35-901)

  • $83.00


FOR BULK ORDER REQUESTS PLEASE CONTACT US

Description :JNK3 inhibitor

Species :

Tag :

Expression System:

Sequence :

CAS Registry Number :1164153-22-3

Molecular Formula :C27H27N5O5

Appearance :Off White powder

Molecular Weight :501.53

Purity :>98% (TLC); NMR (Conforms)

Solubilization :May be dissolved in DMSO (30 mg/ml) or ethanol (10 mg/ml, warm)

Aliases :3-(5-(3-m-Tolylureido)-1H-indazol-1-yl)-N-(3,4,5-trimethoxyphenyl)benzamide

Storage and Stability :Store desiccated as supplied at -20oC temperature for up to 2 years. Store solutions at -20oC for up to 1 month.

Scientific Background :Potent and selective JNK3 inhibitor. IC50= 7 nM and >2800-fold selective over p381. Cell permeable.

References :
1. T Kamenecka et. al J. Biol. Chem. 2009 284:12853

Molecular Structure :

Product Sheets (By Lot #) :

D3370-9.pdf

Research Areas :Apoptosis/Autophagy, Cardiovascular Disease, Cell Cycle, Inflammation, JNK/SAPK Pathway, Neurobiology, NfkB Pathway, Ser/Thr Kinases