SUMO2 Protein(S294-31H)
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Description :Recombinant human SUMO2 (1-93) was expressed in E. coli cells using an N-terminal His tag.
Species :Human
Tag :HIS tag
Expression System:E.coli
Sequence :1-93
Genbank Number :BC008450
Purity :Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability and Shipping :Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Applications :Western Blot
Molecular Weight :~17.5 kDa
Gene Aliases :HSMT3, SMT3B, SMT3H2, SUMO3, Smt3A
Scientific Background :SUMO2 is a member of the SUMO (small ubiquitin-like modifier) protein family which functions in a manner similar to ubiquitin. SUMO2 is bound to target proteins as part of a post-translational modification system and modifies numerous cellular proteins and affect their metabolism and function. SUMO2 is also involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (1). SUMO2 is predominantly detected on nuclear bodies (2).
References :
1. Su, H.-L. et.al: Molecular features of human ubiquitin-like SUMO genes and their encoded proteins. Gene 296: 65-73, 2002.
2. Kamitani, T. et.al: Characterization of a second member of the sentrin family of ubiquitin-like proteins. J. Biol. Chem. 273: 11349-11353, 1998.
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Research Areas :Apoptosis/Autophagy, Cell Cycle, NfkB Pathway, NfkB Pathway, Apoptosis/Autophagy, Cell Cycle