BAFF-R (TNFRSF13C)(B806-40N)

BAFF-R (TNFRSF13C)(B806-40N)

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Description :Recombinant Human BAFF-R (TNFRSF13C) was expressed in E. coli cells.

Species :Human

Tag :

Expression System:E.coli

Sequence :

Genbank Number :Q96RJ3

Storage, Stability and Shipping :The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Applications :Cell Assay

Endotoxin Level :<1.0 EU/μg of recombinant protein as determined by the LAL method.

Molecular Weight :9.0 kDa

Gene Aliases :Tumor necrosis factor receptor superfamily member 13C, TNFRSF13C, B-cell-activating factor receptor, BAFF receptor, BAFFR, BLyS receptor 3, CD_antigen=CD268.

Scientific Background :The B cell-activating factor from the TNF family (BAFF), is emerging as an important regulator of B cell and T cell responses. BAFF was originally identified as a factor responsible for B cell survival and maturation. BAFF binds to several receptors. These include transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI), BAFF-R (BR3), and B cell maturation Ag (BCMA). BAFF-R appears to be particularly important for the regulation of B cell survival and maturation in the spleen, because A/WySnJ mice expressing a defective BAFF-R have disrupted B cell maturation, similar to that seen in BAFF-deficient mice.

Sample Cell Assay Data :

Purity :Recombinant Human BAFF-R (TNFRSF13C) resolved on a 15% SDS-PAGE gel under reducing conditions and stained with Coomassie Brilliant Blue G-250.

Product Sheets (By Lot #) :

G3211-5.pdf

Research Areas :Cancer