Anti-Raptor(R47-363R)
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Description :Rabbit Polyclonal Antibody
Species :
Tag :
Expression System:
Sequence :
Specificity :Recognizes the Raptor protein
Cited Applications :WB, ELISA, ICC
Cross Reactivity :Mouse
Host / Isotype / Clone# :Rabbit, IgG
Immunogen :Raptor (CT) polyclonal antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of mouse Raptor
Purification :Affinity chromatography
Stability :Store at 4oC (add 0.1% NaN3) for several months, and at -20oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Sample Data :Western blot analysis of Raptor in L1210 cell lysate with Raptor antibody at (A) 2 and (B) 4 ug/mL.
Sample Data :Immunocytochemistry of Raptor in L1210 cells with Raptor antibody at 10 ug/mL.
References :
1. Shamji AF et al: Integration of growth factor and nutrient signaling: implications for cancer biology. Mol. Cell 2003; 12:271-80.
2. Fingar DC et al: Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression. Oncogene 2004; 23:3151-71.
3. Yonezawa K et al: Raptor, a binding partner of target of rapamycin. Biochem. Biophys. Res. Commun. 2004; 313:437-441.
4. Hara K et al: Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism. J. Biol. Chem. 1998; 273:14484-94.
Product Sheets (By Lot #) :
Research Areas :Cancer