• $325.00


Description :Rabbit Polyclonal Antibody

Species :

Tag :

Expression System:

Sequence :

Specificity :Recognizes the RIPK3 protein

Cited Applications :WB, ELISA, IF, IHC

Cross Reactivity :Mouse and Rat

Host / Isotype / Clone# :Rabbit, IgG

Immunogen :RIPK3 antibody was raised against a peptide corresponding to amino acids 473 to 486 of murine RIPK3

Purification :Affinity chromatography

Stability :Store at 4oC (add 0.1% NaN3) for several months, and at -20oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Sample Data :Western blot analysis of RIPk3 in mouse 3T3 whole cell lysate in the absence (A) or presence (B) of blocking peptide with RIPk3 antibody at 1 ug/mL.

Sample Data :Immunohistochemistry of RIPK3 in rat kidney tissue with RIPK3 antibody at 5 ug/mL.

References :
1. Yu PW. et al: Identification of RIP3, a RIP-like kinase that activates apoptosis and NFκB. Curr Biol. 1999;9(10):539-42.

2. Sun X et al: RIP3, a novel apoptosis-inducing kinase. J Biol Chem. 1999;274(24):16871-5.

3. Pazdernik NJ et al: Mouse receptor interacting protein 3 does not contain a caspase-recruiting or a death domain but induces apoptosis and activates NF-κB. Mol Cell Bio. 1999; 19(10):6500-8

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Research Areas :Apoptosis/Autophagy, Cancer, Inflammation, JAK/STAT Pathway, JNK/SAPK Pathway, p38 Pathway, Ser/Thr Kinases, Cancer, Inflammation, p38 Pathway, JNK/SAPK Pathway, JAK/STAT Pathway, Apoptosis/Autophagy, Ser/Thr Kinases