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PXK Protein(P99-35G)

PXK Protein(P99-35G)

  • $215.00


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Description :Full-length recombinant human PXK was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Species :Human

Tag :GST tag

Expression System:Sf9 insect cells using baculovirus

Sequence :Full length

Genbank Number :NM_017771

Purity :Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability, and Shipping :Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications :Western Blot

Molecular Weight :~90 kDa

Gene Aliases :FLJ20335; MONaKA

Scientific Background :PX Domain Containing Serine/Threonine Kinase (PXK) is involved in synaptic transmission through modulating brain Na,K-ATPase subunits ATP1B1 and ATP1B3 participate in the ligand-induced internalization and degradation of epidermal growth factors. Mutation of this gene may be associated with susceptibility to systemic lupus erythematosus (SLE).

References :
1. Takeuchi H, et al. Characterization of PXK as a protein involved in epidermal growth factor receptor trafficking. Mol Cell Biol. 30:1689-702, 2010.

2. Zou X, et al. Expression pattern and subcellular localization of five splice isoforms of human PXK. Int J Mol Med. 16:701-7, 2005 Oct.

Product Sheets (By Lot #) :

U1546-5.pdf

Research Areas :Ser/Thr Kinases, Inflammation