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Prolactin (PRL)(P852-40N)

Prolactin (PRL)(P852-40N)

  • $138.00


Description :Recombinant Human Prolactin (PRL) was expressed in E. coli cells.

Species :Human

Tag :

Expression System:E.coli

Sequence :

Genbank Number :P01236

Storage, Stability and Shipping :The lyophilized protein is stable for at least one year from date of receipt at -70oC. Upon reconstitution, this cytokine can be stored in working aliquots at 2o - 8oC for one month, or at -20oC for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Applications :Cell Assay

Endotoxin Level :<1.0 EU/μg of recombinant protein as determined by the LAL method.

Molecular Weight :23.0 kDa

Gene Aliases  :Luterotropic hormone, Lutetropin, Mammotropin, PRL

Reconstitution Protocol :It is recommended to reconstitute lyophilized PRL in sterile distilled water to no less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Scientific Background :Synthesized primarily by the pituitary gland, prolactin is a neuroendocrine hormone that functions to promote and maintain lactation and has also been shown to play a role in breast cancer development, regulation of reproductive function and immune-regulation. While Human prolactin shares only 60% and 63% amino acid sequence identity with mouse and rat prolactin, respectively, the human prolactin receptor can be activated by Rat PRL. abm's Recombinant Human PRL is a single, non-glycosylated polypeptide chain with a molecular mass of 23 kDa.

Sample Cell Assay Data :Determined by its ability to induce the proliferation of rat Nb2-11 cells in the concentration range of 0.1-1.0 ng/ml.

Purity :Recombinant Human Prolactin (PRL) resolved on a 15% SDS-PAGE gel under reducing conditions and stained with Coomassie Brilliant Blue G-250

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Research Areas :Cancer