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PPP2R1A Protein(P162-30H)

PPP2R1A Protein(P162-30H)

  • $314.00


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Description :Recombinant full-length human PPP2R1A was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag.

Species :Human

Tag :His tag

Expression System:Sf9 insect cells using baculovirus

Sequence :Full length

Genbank Number :NM_014225

Purity :Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability, and Shipping :Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications :Western Blot

Molecular Weight :~66 kDa

Gene Aliases :MRD36; PP2A-Aalpha; PP2AAALPHA; PR65A

Scientific Background :PPP2R1A or the PR65 subunit of protein phosphatase 2A (PP2A) acts as a scaffolding protein to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit, together forming the core of heterodimeric PP2A. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis

References :
1. Tang Z, et al: PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation. Dev Cell. 10(5):575-85, 2006.

2. http://www.uniprot.org/uniprot/P30153.

Product Sheets (By Lot #) :

C1899-1.pdf

E3138-9.pdf

Research Areas :Cancer, Phosphatases