Anti-PTK7(P95-63R)
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Description :Rabbit Polyclonal Antibody
Species :
Tag :
Expression System:
Sequence :
Specificity :Recognizes the PTK7 protein
Cited Applications :WB, ELISA, IF, IHC
Cross Reactivity :Human, Mouse and Rat
Host / Isotype / Clone# :Rabbit, IgG
Immunogen :PTK7 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human PTK7
Purification :Affinity chromatography
Stability :Store at 4oC (add 0.1% NaN3) for several months, and at -20oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Sample Data :Western blot analysis of PTK7 in (A) human colon, (B) mouse kidney and (C) rat liver tissue lysate with PTK7 antibody at 1 ug/mL.
Sample Data :Immunohistochemistry of PTK7 in human colon tissue with PTK7 antibody at 2.5 ug/mL.
References :
1. Park SK et al: Characterization of the human full-length PTK7 cDNA encoding a receptor protein kinase-like molecule closely related to chick KLG. J. Biochem.1996; 119:235-9.
2. Lu X et al: PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates. Nature2004; 430:93-8.
3. Easty DJ et al: Loss of expression of receptor tyrosine kinase family genes PTK7 and SEK in metastatic melanoma. Int. J. Cancer1997; 1061-5.
4. Muller-Tidow C et al: High-throughput analysis of genome-wide receptor tyrosine kinase expression in human cancers identifies potential novel drug targets. Clin. Cancer Res.2004; 10:1241-9.
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Research Areas :Cancer, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, Neurobiology, Cancer, Neurobiology, Inflammation, ERK/MAPK Pathway, Invasion/Metastasis