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MYO3 beta, Active(M66-11G)

MYO3 beta, Active(M66-11G)

  • $226.00


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Description :Recombinant human MYO3beta (1-326) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Species :Human

Tag :GST tag

Expression System:Sf9 insect cells using baculovirus

Sequence :1-326

Genbank Number :NM_138995

Specific Activity :Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.

Purity :Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability and Shipping :Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications :Kinase Assay, Western Blot

Molecular Weight :~63 kDa

Gene Aliases :myosin IIIB

Scientific Background :MYO3β is a member of the Class III myosins that are actin-dependent motor proteins containing an amino-terminal kinase domain. MYO3β contains a N-terminal kinase domain, followed by motor, neck, and tail domains. The MYO3β gene generates a variety of splice variants that contain 1 or 2 calmodulin-binding (IQ) motifs in the neck domain and 1 of 3 domains in the tail domain. Northern blot analysis shows expression of a 7-kb MYO3β transcript in the human retina but not in a RPE cell line (1). The MYO3β gene transcript is also detected in the kidney, intestine and testis. The MYO3β gene maps to chromosome 2q31.1-q31.2 by genomic sequence alignment.

References :
1. Dose, A C. et al: A class III myosin expressed in the retina is a potential candidate for Bardet-Biedl syndrome. Genomics 79: 621-624, 2002.

Product Sheets (By Lot #) :

C055-2.pdf

X538-3.pdf

Research Areas :Neurobiology, Ser/Thr Kinases, Neurobiology, Ser/Thr Kinases