MNK1, Active(M54-10G)

MNK1, Active(M54-10G)

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Description :Recombinant full-length human MNK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Species :Human

Tag :GST tag

Expression System:Sf9 insect cells using baculovirus

Sequence :Full Length

Genbank Number :NM_003684

Specific Activity :Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.

Purity :Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability and Shipping :Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications :Kinase Assay, Western Blot

Molecular Weight :~92 kDa

Gene Aliases :MKNK1

Scientific Background :MNK1 (MAP kinase-interacting kinase 2) is a MAP kinase interacting serine/threonine kinase 1 that isolated by a novel expression screening method for identifying the protein kinase substrates (1). Mnk1 expressed in all tissues with the highest level of expression in skeletal muscle (2).

References :
1. Fukunaga, R. et.al: MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates. EMBO J. 16: 1921-1933, 1997.

2. Waskiewicz, A. J. et.al: Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2. EMBO J. 16: 1909-1920, 1997.

Product Sheets (By Lot #) :

I292-2.pdf

N065-3.pdf

Z1336-2.pdf

H2750-7.pdf

Research Areas :Angiogenesis, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, p38 Pathway, Ser/Thr Kinases, Inflammation, ERK/MAPK Pathway, p38 Pathway, Angiogenesis, Invasion/Metastasis, Ser/Thr Kinases