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METTL1 Protein(M321-30G)

METTL1 Protein(M321-30G)

  • $314.00


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Description :Recombinant full-length human METTL1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Species :Human

Tag :GST tag

Expression System:Sf9 insect cells using baculovirus

Sequence :Full length

Genbank Number :NM_005371

Purity :Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability, and Shipping :Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications :Enzyme Function Tests

Molecular Weight :~57 kDa

Gene Aliases :C12orf1; TRM8; TRMT8; YDL201w

Scientific Background :Methyltransferase Like 1 (METTL1) catalyzes the formation of N (7)-methylguanine at position 46 (m7G46) in tRNA. It belongs to the methyltransferase superfamily. METTL1 is involved in the pathway N (7)-methylguanine-tRNA biosynthesis, which is part of tRNA modification.

References :
1. http://www.uniprot.org/uniprot/Q9P0J1.

2. Maj MC, et al: Pyruvate dehydrogenase phosphatase deficiency: identification of the first mutation in two brothers and restoration of activity by protein complementation. J Clin Endocrinol Metab. 90(7):4101-7, 2005.

Product Sheets (By Lot #) :

C2224-3.pdf

Research Areas :Cancer, Neurobiology