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LOXL3 Protein (L263-31G)

LOXL3 Protein (L263-31G)

  • $215.00


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Description :  Recombinant human LOXL3 (526-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Species : Human

Tag : GST tag

Expression System : Sf9 insect cells using baculovirus

Sequence : 526-end

Genbank Number : NM_032603

Purity : Sample Purity Data. For specific information on a given lot, see related technical data sheet. 

Storage, Stability and Shipping : Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications : Western Blot

Molecular Weight : ~54 kDa

Gene Aliases : LOXL

Scientific Background : LOXL3 is a member of the lysyl oxidase gene family. This family is essential to the biogenesis of connective tissue. The lysyl oxidase gene family encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin (1). LOXL3 is highly expressed in central nervous system, uterus, heart, and leukocyte (1). LOXL3 plays an important role in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis.

References : 
1. Zhong, Z. et al: Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science. 1994 Apr 1;264(5155):95-8.

2. Tian, S. S. et al: Rapid activation of the STAT3 transcription factor by granulocyte colony-stimulating factor. Blood. 1994 Sep 15;84(6):1760- P53.

Product Sheets: (by Lot #):

J583-2.pdf

Research Areas : Cancer, Metabolic Disorder,