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LH-846(C67-901)

  • $83.00


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Description :Casein Kinase 1δ inhibitor

Species :

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Expression System:

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CAS Registry Number :639052-78-1

Molecular Formula :C16H13ClN2OS

Appearance :White crystalline powder

Molecular Weight :318.81

Purity :>98% (TLC); NMR (Conforms)

Solubilization :May be dissolved in DMSO (20 mg/ml) or ethanol (5 mg/ml, warm)

Aliases :N-(5-Chloro-6-methyl-2-enzothiazolyl)benzeneacetamide

Storage and Stability :Store desiccated as supplied at ambient temperature for up to 2 years. Store solutions at -20oC for up to 3 months.

Scientific Background :Selective inhibitor of casein kinase (CK) 1δ, IC50s=0.29, 1.3 and 2.5 µM for δ, ε and α isoforms respectively with no inhibition of CK2. Inhibits CK1δ-mediated phosphorylation.

References :
1. JW Lee et al. Angew. Chem. Int. Ed. Engl. 2011 50:10608

Molecular Structure :

Product Sheets (By Lot #) :

D3370-5.pdf

Research Areas :