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JNK Inhibitor IX(M34-901)

JNK Inhibitor IX(M34-901)

  • $83.00


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Description :JNK inhibitor

Species :

Tag :

Expression System:

Sequence :

CAS Registry Number :312917-14-9

Molecular Formula :C20H16N2OS

Appearance :Off-White powder

Molecular Weight :332.4

Purity :>98% (TLC); NMR (Conforms)

Solubilization :May be dissolved in DMSO (13mg/ml); or ethanol (4 mg /ml, warm)

Aliases :N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)-1-naphthalenecarboxamide

Storage and Stability :Store desiccated as supplied at ambient temperature for up to 2 years. Store solutions at -20oC for up to 3 months.

Scientific Background :Inhibits JNK2 and JNK3 via binding to the ATP binding domain. Displays little or no activity against JNK1, p38 and a panel of 30 other kinases1.

References :
1. RM Angell et al. Bioorg. Med. Chem. Lett. 2007 17:1296

Molecular Structure :

Product Sheets (By Lot #) :

D3370-14.pdf

Research Areas :Apoptosis/Autophagy, Cardiovascular Disease, Cellular Stress, Inflammation, JNK/SAPK Pathway, Neurobiology, NfkB Pathway, Ser/Thr Kinases