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IL-2(I862-40N)

IL-2(I862-40N)

  • $204.00


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Description :Human active form IL-2 (21-153) was expressed in E. coli cells and purified by proprietary chromatographic techniques.

Species :Human

Tag :

Expression System:E.coli

Sequence :21-153

Genbank Number :NP_000577.2

Activity Assay :Sample Biological Activity Plot. For specific information on a given lot, see related technical data sheet.

Purity :Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability and Shipping :Stored at desiccated below -20oC. It is stable at 4oC between 2-7 days. For long term storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications :Cell Assay

Endotoxin Level :Less than 0.1 ng/ug (IEU/ug) of IL-2.

Molecular Weight :~14.5 kDa

Gene Aliases :TCGF; lymphokine; IL2

Scientific Background :IL-2 or interleukin 2 is a secreted cytokine which referred to as T-cell growth factor, that is a powerfully immunoregulatory lymphokine that is produced by lectin- or antigen-activated T cells. IL2 can act as a growth hormone that is important for the proliferation of T and B-lymphocytes (1). IL2 expression is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene (2).

References :
1. Lowenthal, J. W. et.al: Similarities between interleukin-2 receptor number and affinity on activated B and T lymphocytes. Nature 315: 669-672, 1985.

2. Hollander, G. A. et.al: Monoallelic expression of the interleukin-2 locus. Science 279: 2118-2121, 1998.

Product Sheets (By Lot #) :

I111-9.pdf

Research Areas :AKT/PKB Pathway, ERK/MAPK Pathway, Inflammation, JAK/STAT Pathway, JNK/SAPK Pathway, NfkB Pathway, p38 Pathway, PKA/PKC Pathway, Inflammation, AKT/PKB Pathway, ERK/MAPK Pathway, p38 Pathway, JNK/SAPK Pathway, NfkB Pathway, JAK/STAT Pathway, PKA/PKC Pathway