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GNA11 Protein(G116-30G)

GNA11 Protein(G116-30G)

  • $215.00


Description :Full-length recombinant human GNA11 protein was expressed in E.coli cells using an N-terminal GST tag.

Species :Human

Tag :GST tag

Expression System:E.coli

Sequence :Full length

Genbank Number :NM_002067

Purity :Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability, and Shipping :Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications :Enzyme Assay, Western Blot

Molecular Weight :66 kDa

Gene Aliases :FBH; FBH2; FHH2; GNA-11; HHC2; HYPOC2

Scientific Background :Guanine nucleotide-binding proteins (G proteins) are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits, and function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. Guanine nucleotide-binding protein subunit alpha-11 (GNA11) acts as an activator of phospholipase C. Involved in signaling of gonadotropin-releasing hormone receptor, negatively regulating cell growth. Down-regulation may be involved in human breast cancers.

References :


Product Sheets (By Lot #) :


Research Areas :Cancer, Cardiovascular Disease