DMPQ 2 HCl(P13-901)

DMPQ 2 HCl(P13-901)

  • $72.00


FOR BULK ORDER REQUESTS PLEASE CONTACT US

Description :PDGFR beta inhibitor

Species :

Tag :

Expression System:

Sequence :

CAS Registry Number :137206-97-4

Molecular Formula :C16H14N2O2 ∙2HCl

Appearance :Yellow powder

Melting Point :231-234oC

Molecular Weight :339.2

Purity :>98% (TLC); NMR (Conforms)

Solubilization :May be dissolved in Water (30 mg/ml) or DMSO (1 mg/ml, warm)

Aliases :5,7-Dimethoxy-3-(4-pyridinyl) quinoline dihydrochloride

Storage and Stability :Store desiccated as supplied at room temperature for up to 2 years. Store solutions at -20oC for up to 3 months.

Scientific Background :A potent and selective inhibitor of PDGFRβ, IC50=80 nM. Greater than 100-fold more selective compared to EGFR, erB2, p56, PKA and PKC. Cell permeable.

References :
1. RE Dolle et al. J.Med. Chem. 1994 37:2627

Molecular Structure :

Product Sheets (By Lot #) :

T2257-39.pdf

Research Areas :AKT/PKB Pathway, Cancer, ERK/MAPK Pathway, Receptor Tyrosine Kinases, Cancer, AKT/PKB Pathway, ERK/MAPK Pathway, Receptor Tyrosine Kinases