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CK1 gamma 1, Active(C68-11G)

CK1 gamma 1, Active(C68-11G)

  • $226.00


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Description :Recombinant human CK1 gamma 1 (21-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Species :Human

Tag :GST tag

Expression System:Sf9 insect cells using baculovirus

Sequence :21-end

Genbank Number :NM_022048

Specific Activity :Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.

Purity :Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability and Shipping :Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications :Kinase Assay, Western Blot

Molecular Weight :~70-76 kDa

Gene Aliases :CK1G1; CSNK1G1; CKI-gamma 1

Scientific Background :CK1γ1 or casein kinase 1, gamma 1 is belonging to the most abundant serine/threonine kinase in eukaryotic cell extracts which is mainly involved in growth and morphogenesis of eukaryotic cells. Casein kinase 1, gamma 1 possesses a C-terminal most terminal sequence motif (MTM), which it shares with CSNK1G2 and CSNK1G3 which is associated with heterologous carboxy-terminal sequences (1). Casein kinase 1-gamma couples Wnt receptor activation to the cytoplasmic signal transduction apparatus (2).

References :
1. Kusuda, J. et.al: Cloning, expression analysis and chromosome mapping of human casein kinase 1 gamma-1 (CSNK1G1): identification of two types of cDNA encoding the kinase protein associated with heterologous carboxy-terminal sequences. Cytogenet. Cell Genet. 90: 298-302, 2000.

2. Davidson, G. et.al: Casein kinase 1-gamma couples Wnt receptor activation to cytoplasmic signal transduction. Nature 438: 867-872, 2005.

Product Sheets (By Lot #) :

S250-2.pdf

Research Areas :Cancer, Inflammation, Neurobiology, NfkB Pathway, Ser/Thr Kinases, WNT Signaling, Cancer, Neurobiology, Inflammation, NfkB Pathway, WNT Signaling, Ser/Thr Kinases