Chaetocin(K421-904C)

Chaetocin(K421-904C)

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Description :Lys Methyltransferase Inhibitor

Species :

Tag :

Expression System:

Sequence :

CAS Registry Number :28097-03-2

Molecular Formula :C30H28N6O6S4

Appearance :Lyophilized solid

Melting Point :196.1-197.8oC

Molecular Weight :696.9

Purity :>99%

Solubilization :May be dissolved in DMSO (25 mg/ml); or ethanol (25 mg/ml)

Aliases :Lys methyltransferase inhibitor

Storage and Stability :Store desiccated as supplied at -20oC for up to 2 years. Store solutions at -20oC for up to 1 month

Scientific Background :Inhibits the lysine methyltransferase SU (VAR)3-91. Displays antimyeloma activity in IL-6-dependent myeloma cell lines2. Cell permeable.

References :
1. D Greiner et al. Nat. Chem. Biol. 2005 1:143

2. CR Isham et al. Blood 2007 109:2579

Molecular Structure :

Product Sheets (By Lot #) :

P3320-10.pdf

Research Areas :Cancer, Cell Cycle, Inflammation