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CCL21(E882-40N)

CCL21(E882-40N)

  • $248.00


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Description :Recombinant Human CCL21 was expressed in E. coli cells.

Species :Human

Expression System:E.coli

Genbank Number :O00585

Storage, Stability and Shipping :The lyophilized protein is stable for at least one year from date of receipt at -70oC. Upon reconstitution, this cytokine can be stored in working aliquots at 2o - 8oC for one month, or at -20oC for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Applications :Cell Assay

Endotoxin Level :<1.0 EU/μg of recombinant protein as determined by the LAL method.

Molecular Weight :12.0 kDa

Gene Aliases :C-C motif chemokine 21, 6Ckine, Beta-chemokine exodus-2, SLC, Small-inducible cytokine A21, SCYA21, Recombinant Human Secondary Lymphoid-Tissue Chemokine (CCL21).

Reconstitution Protocol :A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Scientific Background :CCL21, which is a member of the family of CC-Chemokines, has a unique 36 (murine) or 37 (human) amino acid carboxyl-terminal extension not seen in other chemokines. CCL21 selectively stimulates the chemotaxis of adult T lymphocytes and is expressed preferentially in lymph node tissue. CCL21 is critical for adult T cell adhesion to high endothelial venules in lymph nodes, a rate-limiting step for T cell trafficking through nodal tissue.

Sample Cell Assay Data :Determined by its ability to chemoattract total lymphocyte population using a concentration range of 10-100 ng/mL.

Purity :Recombinant Human CCL21 resolved on a 17% SDS-PAGE gel under reducing conditions and stained with Coomassie Brilliant Blue G-250

Product Sheets (By Lot #) :

G3211-12.pdf

Research Areas :Cancer