• $595.00


Description :Rabbit Polyclonal Antibody

Species :

Tag :

Expression System:

Sequence :

Specificity :Recognizes the p16INK4A protein

Cited Applications :WB, ELISA, IF, IHC

Cross Reactivity :Human, Mouse and Rat

Host / Isotype / Clone# :Rabbit, IgG

Immunogen :p16INK4A antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human p16INK4A

Purification :Affinity chromatography

Stability :Store at 4oC (add 0.1% NaN3) for several months, and at -20oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Sample Data :Western blot analysis of p16INK4A in mouse colon tissue lysate with p16INK4A antibody at (A) 1 and (B) 2 ug/mL.

Sample Data :Immunohistochemistry of p16INK4A in human colon tissue with p16INK4A antibody at 10 ug/mL.

References :
1. Stone S et al: Complex structure and regulation of the p16(MTS1) locus. Cancer Res.1995; 55:2988-94.

2. Kamb A et al: Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus. Nature Genet.1994; 8:22-6.

3. Kratzke RA et al: Immunohistochemical analysis of the p16 (INK4) cyclin-dependent kinase inhibitor in malignant mesothelioma. J. Nat. Cancer Inst.1995; 87:1870-5.

4. Stott FJ et al: The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2. EMBO J.1998; 17:5001-14.

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Research Areas :Cancer, Cell Cycle, Cancer, Cell Cycle