Anti-2019-nCoV Spike (mFc) (C19S1-61MH)

Anti-2019-nCoV Spike (mFc) (C19S1-61MH)

  • $165.00


Description :Recombinant monoclonal antibody with human Fab and mouse Fc region that can be detected with conjugated anti-mouse antibody in immunoassays.

Species :Human

Expression System:CHO cells

Specificity :Recognizes the 2019-nCoV Spike protein

Cited Applications :ELISA
Ideal working dilutions for each application should be empirically determined by the investigator.

Cross Reactivity :SARS-CoV spike protein

Host / Isotype / Clone# :Human Fab-mouse Fc

Aliases :Anti-SARS-CoV 2 Spike Protein Antibody

Stability :1yr at –20oC from date of shipment
Store product at –20oC. For optimal storage, aliquot antibody into smaller quantities after centrifugation and store at recommended temperature. For optimal performance, avoid repeated handling and multiple freeze/thaw cycles. Product shipped on ice packs.

Scientific Background :The severe acute respiratory syndrome related novel coronavirus SARS-CoV-2 has caused the pandemic of the respiratory diseases (COVID-19) around the world in 2020 (1). The spike glycoprotein (S) of coronavirus belongs to the type I transmembrane protein containing two subunits, S1 and S2 (2), which is also known to be the key component to bind with host cells through the interaction with angiotensin-converting enzyme 2 (ACE2) (3). A receptor binding domain (RBD) of S1 can recognize the cell surface receptor and the mutation of RBD could cause higher motility rate (3).

Assay Data :Binding of Human anti-2019-nCoV spike (mFc) (C19S1-61MH) to immobilized 2019-nCoV Spike protein RBD (C19SD-G241H) determined by ELISA using Goat anti-human Fab and Goat anti-mouse IgG (G32-62G) secondary antibodies.

Product Sheets (By Lot #) :