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BML-278 (S35-904C)

BML-278 (S35-904C)

  • $72.00


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Description :  SIRT1 Activator

CAS Registry Number: N/F

Molecular Formula : C24H25NO4

Appearance : Off white powder

Melting Point : 141-143oC

Molecular Weight : 391.5

Purity :  >98% (TLC)

Solubilization : May be dissolved in DMSO (5 mg/ml).

Aliases : N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine

Stability : Store desiccated as supplied at room temperature for up to 2 years. Store solutions at -20oC for up to 3 months.

Scientific Background : A structurally novel activator of SIRT1 (EC150=1 μM). Displays selectivity over SIRT2 and 3 (EC150=25 and 50 μM respectively). Cell permeable.

References : 
1. A Mai et al. J. Med. Chem. 2009 52:5496

Molecular Structure : Sample Purity Data. For specific information on a given lot, see related technical data sheet. 

Product Sheets (By Lot #):

P3320-7.pdf