BML-210(H83-904C)

BML-210(H83-904C)

  • $259.00


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Description :HDAC Inhibitor

Species :

Tag :

Expression System:

Sequence :

CAS Registry Number :537034-17-6

Molecular Formula :C20H25N3O2

Appearance :Tan powder

Melting Point :168-170oC

Molecular Weight :339.4

Purity :98%

Solubilization :May be dissolved in DMSO (25 mg/ml); or ethanol (10 mg/ml, warm)

Aliases :N1-(2-aminophenyl)-N8-phenyloctanediamide

Storage and Stability :Store desiccated as supplied at 4oC for up to 2 years. Store solutions at -20oC for up to 3 months

Scientific Background :A novel non-hydroxamic acid HDAC inhibitor. IC50=5-10 uM (HeLa nuclear extract). Induces growth inhibition, proapoptotic and differentiation effects on human leukemia cell lines.

References :
1. J. Savickiene et al. Eur. J. Pharmacol. 2006 549 9

2. D. Herman et al. Nature Chem. Biol. 2006 10 551

Molecular Structure :

Product Sheets (By Lot #) :

P3320-6.pdf

Research Areas :Cancer, Cell Cycle, Inflammation