Anti-Phosphoserine (Anti-pS), Biotin Conjugated(S95-65BR)
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Description :Rabbit Polyclonal Antibody
Specificity :Recognizes peptides and proteins phosphorylated on serine residues.
Cited Applications :WB, ELISA
Cross Reactivity :Pan-specific antibody. No cross-reactions detected with phosphotyrosine. Slight reaction with phosphothreonine.
Immunogen :Phosphoserine peptide-KLH conjugates
Purification :Affinity chromatography
Stability :Store at 4oC (add 0.1% NaN3) for several months, and at -20oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For optimal performance, avoid repeated handling and multiple freeze/thaw cycles.
Scientific Background :Post-translational modification of proteins and peptides is a robust way to regulate function of existing proteins or peptides. Methylation on lysine residues is one example of post-translational modification and is performed by a variety of protein methyl transferases in the cell. C/EBPs are extensively modified by methylation of lysine side chains and this regulated methylation profoundly affects the activity of C/EBPs (1). The Methylated Lysine antibody detects methylation on lysine residues in proteins and peptide.
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Research Areas :AKT/PKB Pathway, Angiogenesis, Apoptosis/Autophagy, Cancer, Cell Cycle, Cellular Stress, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, JAK/STAT Pathway, JNK/SAPK Pathway, Metabolic Disorder, Neurobiology, NfkB Pathway, p38 Pathway, PKA/PKC Pathway, WNT Signaling, Cancer, Neurobiology, Inflammation, Metabolic Disorder, Cardiovascular Disease, AKT/PKB Pathway, ERK/MAPK Pathway, p38 Pathway, JNK/SAPK Pathway, NfkB Pathway, JAK/STAT Pathway, PKA/PKC Pathway, WNT Signaling, Apoptosis/Autophagy, Cell Cycle, Cellular Stress, Angiogenesis, Invasion/Metastasis