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Anti-KDM6B(K426-63BR)

Anti-KDM6B(K426-63BR)

  • $325.00


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Description :Rabbit Polyclonal Antibody

Species :

Tag :

Expression System:

Sequence :

Specificity :Recognizes the KDM6B protein

Cited Applications :WB, ELISA, ICC, IF

Cross Reactivity :Human, Mouse and Rat

Host / Isotype / Clone# :Rabbit, IgG

Immunogen :KDM6B antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human KDM6B

Purification :Affinity chromatography

Stability :Store at 4oC (add 0.1% NaN3) for several months, and at -20oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Sample Data :Western blot analysis of KDM6B in K562 cell lysate with KDM6B antibody at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide.

Sample Data :Immunocytochemistry of KDM6B in K562 cells with KDM6B antibody at 2.5 ug/mL.

References :
1. Lai F et al: cDNA cloning and genomic structure of three genes localized to human chromosome band 5q31 encoding potential nuclear proteins. Genomics2000; 70:123-30.

2. Agger K et al: UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nature 2007; 449:731-4.

3. De Santa F et al: The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated silencing. Cell 2007; 130:1083-94

4. Sola S et al: p53 interaction with JMJD3 results in its nuclear distribution during mouse neural stem cell differentiation. PLoS One 2011; 6:e18421.

Product Sheets (By Lot #) :

O2361-31.pdf

Research Areas :Cancer, Cell Cycle, Inflammation, Cancer, Inflammation, Cell Cycle