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Description :Rabbit Polyclonal Antibody
Specificity :Recognizes the APC13 protein
Cited Applications :WB, ELISA, IF
Cross Reactivity :Human, Mouse and Rat
Host / Isotype / Clone# :Rabbit, IgG
Immunogen :APC13 antibody was raised against a 17 amino acid synthetic peptide near the center of human APC13
Formulation :PBS + 0.02% sodium azide.
Purification :Affinity chromatography
Stability :Store at 4oC (add 0.1% NaN3) for several months, and at -20oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Sample Data :Western blot analysis of APC13 in Jurkat cell tissue lysate with APC13 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
1. Peters JM: The anaphase promoting complex/cyclosome: a machine designed to destroy. Nat. Rev. Mol. Cell Biol.2006; 7:644-56.
2. Jorgensen PM et al: Characterisation of the human APC1, the largest subunit of the anaphase-promoting complex. Gene2001; 262:51-9.
3. Schwickart M et al: Swm1/Apc13 is an evolutionarily conserved subunit of the anaphase-promoting complex stabilizing the association of Cdc16 and Cdc27. Mol. Cell. Biol.2004; 24:3562-76.
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Research Areas :Cancer, Cell Cycle, Neurobiology, p38 Pathway, Cancer, Neurobiology, p38 Pathway, Cell Cycle