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Description :Rabbit Polyclonal Antibody
Specificity :Recognizes the APC1 protein
Cited Applications :WB, ELISA, IHC
Cross Reactivity :Human and Mouse
Host / Isotype / Clone# :Rabbit, IgG
Immunogen :APC1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human APC1
Purification :Affinity chromatography
Stability :Store at 4oC (add 0.1% NaN3) for several months, and at -20oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Sample Data :Western blot analysis of APC1 in SK-N-SH cell lysate with APC1 antibody at (A) 1 and (B) 2 ug/mL.
Sample Data :Immunohistochemistry of APC1 in human brain tissue with APC1 antibody at 5 ug/mL.
1. Yu PW. etal: Identification of RIP3, a RIP-like kinase that activates apoptosis and NFκB. Curr Biol. 1999;9(10):539-42.
2. Peters JM: The anaphase promoting complex/cyclosome: a machine designed to destroy. Nat. Rev. Mol. Cell Biol.2006; 7:644-56.
3. Jorgensen PM et al: Characterisation of the human APC1, the largest subunit of the anaphase-promoting complex. Gene2001; 262:51-9.
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Research Areas :Cancer, Cell Cycle, Neurobiology, p38 Pathway, Cancer, Neurobiology, p38 Pathway, Cell Cycle