AITRL (TNFSF18) (A828-40N)

AITRL (TNFSF18) (A828-40N)

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Description :Recombinant Human AITRL (TNFSF18) was expressed in E. coli cells.

Species :Human

Tag :

Expression System:E.coli

Sequence :

Genbank Number :Q9UNG2

Formulation :Lyophilized from a 0.2 micron filtered solution in Tris and salt.

Storage, Stability and Shipping :The lyophilized protein is stable for at least one year from date of receipt at -70oC. Upon reconstitution, this cytokine can be stored in working aliquots at 2o - 8oC for one month, or at -20oC for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Applications :Cell Assay

Endotoxin Level :<1.0 EU/μg of recombinant protein as determined by the LAL method.

Molecular Weight :14.2 kDa

Gene Aliases :Activation-inducible TNF-related ligand, AITRL, Glucocorticoid-induced TNF-related ligand, GITRL, hGITRL, Tumor necrosis factor ligand superfamily member 18, TNFSF18, TL-6, Recombinant Human Activation-Induced TNFR Member Ligand (TNFSF18).

Reconstitution Protocol :Reconstitute at 0.1 mg/mL in PBS containing at least 0.1% human or bovine serum albumin.

Scientific Background :TNFSF18 is a transmembrane glycoprotein which is expressed in vascular endothelial cells as well as neurons, antigen presenting cells, CD4­- CD8- double negative thymic precursors, and in the eye. TNFSF18 works to mediate the interactions between T cells and endothelial cells, and T cell growth. It has been shown that TNFSF18's expression is transiently up-regulated by proinflammatory stimulation.

Sample Cell Assay Data :

Purity :Recombinant Human AITRL (TNFSF18) resolved on a 17% SDS-PAGE gel under reducing conditions and stained with Coomassie Brilliant Blue G-250.

Product Sheets (By Lot #) :

G3211-3.pdf

Research Areas :Cancer