Anti-APC6(A92-363R)
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Description :Rabbit Polyclonal Antibody
Species :
Tag :
Expression System:
Sequence :
Specificity :Recognizes the APC6 protein
Cited Applications :WB, ELISA, IF, IHC
Cross Reactivity :Human, Mouse and Rat
Host / Isotype / Clone# :Rabbit, IgG
Immunogen :APC6 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human APC6
Purification :Affinity chromatography
Stability :Store at 4oC (add 0.1% NaN3) for several months, and at -20oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Sample Data :Western blot analysis of APC6 in human liver tissue lysate with APC6 antibody at (A) 1 and (B) 2 ug/mL.
Sample Data :Immunohistochemistry of APC6 in human liver tissue with APC6 antibody at 5 ug/mL.
References :
1. Peters JM: The anaphase promoting complex/cyclosome: a machine designed to destroy. Nat. Rev. Mol. Cell Biol.2006; 7:644-56.
2. Jorgensen PM et al: Characterisation of the human APC1, the largest subunit of the anaphase-promoting complex. Gene2001; 262:51-9.
3. Wang J et al: Insights into anaphase promoting complex TPR subdomain assembly from a CDC26-APC structure. Nat. Struct. Mol. Biol.2009; 16:987-9.
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Research Areas :Cancer, Cell Cycle, Neurobiology, p38 Pathway, Cancer, Neurobiology, p38 Pathway, Cell Cycle