SOD3 Protein (S28-31G)
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Description : Recombinant full-length human SOD3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Species : Human
Tag : GST tag
Expression System : Sf9 insect cells using baculovirus
Sequence : Full Length
Genbank Number : NM_003102
Purity : Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability and Shipping : Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Applications : Western Blot
Molecular Weight : 52 kDa
Gene Aliases : EC-SOD
Scientific Background : Extracellular superoxide dismutase [Cu-Zn] (SOD3) protects the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. Although the function of SOD3 as a regulator of cellular growth has been well established, the role of SOD3 in tumorigenesis is still unclear.
References :
1. S. Marklund, (1973). A novel superoxide dismutase of high molecular weight from bovine liver,” Acta Chemica Scandinavica, 27,1458–1460.
2. Laukkanen MO. (2016). Extracellular Superoxide Dismutase: Growth Promoter or Tumor Suppressor? Oxid Med Cell Longev. 2016:3612589
3. http://www.uniprot.org/uniprot/P08294
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Research Areas : Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Cellular Stress, Inflammation, Neurobiology,