T4 UvsY Protein T4SY-C501H

T4 UvsY Protein T4SY-C501H

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Description : Recombinant full-length T4 UvsY Protein from Escherichia virus T4 was expressed in E. coli using an N-terminal His-tag.

Species : Escherichia virus

Tag : HIS-free

Expression System: E.coli

Genbank Number : X04856

Purity :Sample Purity Data. For specific information on a given lot, see related technical data sheet.

 

Storage, Stability and Shipping : Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Molecular Weight : 18 kDa

Gene Aliases : Bacteriophage T4 DNA repair gene uvsY, recombination protein uvsY

Scientific Background : UvsY is a bacteriophage T4 recombination mediator protein (RMP) which promotes homologous recombination. UvsY exists in solution predominantly as a hexamer, and binds to ssDNA in this form. UvsY facilitates assembly of presynaptic filaments by loading UvsX recombinase onto ssDNA and the concomitant displacement of Gp32 ssDNA-binding protein from ssDNA (1,2).

References :

  1. Liu, J. et al: Mechanism of presynaptic filament stabilization by the bacteriophage T4 UvsY recombination mediator protein. Biochemistry, 2006; 45(17): 5493–5502.
  2. Liu, J. et al: Assembly and dynamics of the bacteriophage T4 homologous recombination machinery. Virol J, 2010; 7:357.

Product Sheets (By Lot #) :

J4005-6